diff --git a/icu4c/source/test/intltest/loctest.cpp b/icu4c/source/test/intltest/loctest.cpp
index 9fe056fe0e7..546b49006cc 100644
--- a/icu4c/source/test/intltest/loctest.cpp
+++ b/icu4c/source/test/intltest/loctest.cpp
@@ -5592,17 +5592,12 @@ public:
     }
 };
 
-
 bool isKnownSourceForCLDR17099(const std::string& s) {
     if (s.compare("qaa-Cyrl-CH") == 0) {
         return true;
     }
-    if (s.compare(0, 9, "und-Latn-") != 0) {
-        return false;
-    }
-    std::string tail(s.substr(9));
-    std::string regionsForCLDR17099("AE CC ER HK IL IN MV PK RS SD SS");
-    return (regionsForCLDR17099.find(tail) != std::string::npos);
+    
+	return false;
 }
 
 void U_CALLCONV
@@ -5615,7 +5610,7 @@ testLikelySubtagsLineFn(void *context,
     (void)fieldCount;
     LocaleTest* THIS = (LocaleTest*)context;
     std::string source(trim(std::string(fields[0][0], fields[0][1]-fields[0][0])));
-    if (isKnownSourceForCLDR17099(source) && THIS->logKnownIssue("CLDR-17099", "likelySubtags.txt wrong for certain und-Latn-XX locales")) {
+    if (isKnownSourceForCLDR17099(source) && THIS->logKnownIssue("CLDR-17099", "likelySubtags.txt wrong for qaa-Cyrl-CH")) {
         return;
     }
     std::string addLikely(trim(std::string(fields[1][0], fields[1][1]-fields[1][0])));
diff --git a/icu4c/source/test/intltest/transrt.cpp b/icu4c/source/test/intltest/transrt.cpp
index c3426759989..6f9200ea4b0 100644
--- a/icu4c/source/test/intltest/transrt.cpp
+++ b/icu4c/source/test/intltest/transrt.cpp
@@ -1240,9 +1240,6 @@ void TransliteratorRoundTripTest::TestHebrew() {
     delete legal;
 }
 void TransliteratorRoundTripTest::TestCyrillic() {
-    if (logKnownIssue("CLDR-17026", "Remaining roundtrip issues with new Cyrillic-Latin transform")) {
-        return;
-    }
     RTTest test("Latin-Cyrillic");
     Legal *legal = new Legal();
 
diff --git a/icu4j/main/common_tests/src/test/java/com/ibm/icu/dev/test/util/ULocaleTest.java b/icu4j/main/common_tests/src/test/java/com/ibm/icu/dev/test/util/ULocaleTest.java
index da2b4707f35..5f1903a28a2 100644
--- a/icu4j/main/common_tests/src/test/java/com/ibm/icu/dev/test/util/ULocaleTest.java
+++ b/icu4j/main/common_tests/src/test/java/com/ibm/icu/dev/test/util/ULocaleTest.java
@@ -5420,16 +5420,6 @@ public class ULocaleTest extends TestFmwk {
 
     }
 
-    final List<String> regionsForCLDR17099 = Arrays.asList("AE", "CC", "ER", "HK", "IL", "IN", "MV", "PK", "RS", "SD", "SS");
-
-    boolean isKnownSourceForCLDR17099(String s) {
-        if (!s.startsWith("und-Latn-")) {
-            return false;
-        }
-        String tail = s.substring(9);
-        return regionsForCLDR17099.contains(tail);
-    }
-
     private static final class TestCase implements Cloneable {
         private static final String ENDL = System.getProperties().getProperty("line.separator");
 
@@ -5483,28 +5473,27 @@ public class ULocaleTest extends TestFmwk {
     @Parameters(method = "readLikelySubtagsTestCases")
     public void likelySubtagsDataDriven(TestCase test) {
         ULocale l = ULocale.forLanguageTag(test.source);
-        if (!isKnownSourceForCLDR17099(test.source) && !logKnownIssue("CLDR-17099", "likelySubtags.txt wrong for certain und-Latn-XX locales")) {
-            if (test.addLikely.equals("FAIL")) {
-                assertEquals("addLikelySubtags(" + test.source + ") should be unchanged",
-                    l, ULocale.addLikelySubtags(l));
-            } else {
-                assertEquals("addLikelySubtags(" + test.source + ")",
-                    test.addLikely, ULocale.addLikelySubtags(l).toLanguageTag());
-            }
-            if (test.removeFavorRegion.equals("FAIL")) {
-                assertEquals("minimizeSubtags(" + test.source + ") should be unchanged",
-                    l, ULocale.minimizeSubtags(l));
-            } else {
-                assertEquals("minimizeSubtags(" + test.source + ")",
-                    test.removeFavorRegion, ULocale.minimizeSubtags(l).toLanguageTag());
-            }
-            if (test.removeFavorScript.equals("FAIL")) {
-                assertEquals("minimizeSubtags(" + test.source + ") - FAVOR_SCRIPT should be unchanged",
-                    l, ULocale.minimizeSubtags(l, ULocale.Minimize.FAVOR_SCRIPT));
-            } else {
-                assertEquals("minimizeSubtags(" + test.source + ") - FAVOR_SCRIPT",
-                    test.removeFavorScript, ULocale.minimizeSubtags(l, ULocale.Minimize.FAVOR_SCRIPT).toLanguageTag());
-            }
+
+        if (test.addLikely.equals("FAIL")) {
+            assertEquals("addLikelySubtags(" + test.source + ") should be unchanged",
+                l, ULocale.addLikelySubtags(l));
+        } else {
+            assertEquals("addLikelySubtags(" + test.source + ")",
+                test.addLikely, ULocale.addLikelySubtags(l).toLanguageTag());
+        }
+        if (test.removeFavorRegion.equals("FAIL")) {
+            assertEquals("minimizeSubtags(" + test.source + ") should be unchanged",
+                l, ULocale.minimizeSubtags(l));
+        } else {
+            assertEquals("minimizeSubtags(" + test.source + ")",
+                test.removeFavorRegion, ULocale.minimizeSubtags(l).toLanguageTag());
+        }
+        if (test.removeFavorScript.equals("FAIL")) {
+            assertEquals("minimizeSubtags(" + test.source + ") - FAVOR_SCRIPT should be unchanged",
+                l, ULocale.minimizeSubtags(l, ULocale.Minimize.FAVOR_SCRIPT));
+        } else {
+            assertEquals("minimizeSubtags(" + test.source + ") - FAVOR_SCRIPT",
+                test.removeFavorScript, ULocale.minimizeSubtags(l, ULocale.Minimize.FAVOR_SCRIPT).toLanguageTag());
         }
     }
 }