diff --git a/icu4c/source/test/intltest/idnaref.cpp b/icu4c/source/test/intltest/idnaref.cpp
index 03d516cea42..e0991ae4ae3 100644
--- a/icu4c/source/test/intltest/idnaref.cpp
+++ b/icu4c/source/test/intltest/idnaref.cpp
@@ -16,8 +16,7 @@
 
 #include "unicode/utypes.h"
 
-#if !UCONFIG_NO_IDNA
-
+#if !UCONFIG_NO_IDNA && !UCONFIG_NO_TRANSLITERATION
 #include "idnaref.h"
 #include "strprep.h"
 #include "punyref.h"
@@ -987,5 +986,4 @@ CLEANUP:
 
     return result;
 }
-
 #endif /* #if !UCONFIG_NO_IDNA */
diff --git a/icu4c/source/test/intltest/itmajor.cpp b/icu4c/source/test/intltest/itmajor.cpp
index bf00b86881b..9faedbef2e8 100644
--- a/icu4c/source/test/intltest/itmajor.cpp
+++ b/icu4c/source/test/intltest/itmajor.cpp
@@ -139,7 +139,7 @@ void MajorTestLevel::runIndexedTest( int32_t index, UBool exec, const char* &nam
 #endif
                 break;
         case 10: name = "idna";
-#if !UCONFIG_NO_IDNA
+#if !UCONFIG_NO_IDNA  && !UCONFIG_NO_TRANSLITERATION
             if(exec){
                 logln("TestSuite IDNA----"); logln();
                 TestIDNA test;
diff --git a/icu4c/source/test/intltest/nptrans.cpp b/icu4c/source/test/intltest/nptrans.cpp
index 4ec67707ae1..6fcde250160 100644
--- a/icu4c/source/test/intltest/nptrans.cpp
+++ b/icu4c/source/test/intltest/nptrans.cpp
@@ -16,6 +16,7 @@
 
 #include "unicode/utypes.h"
 
+#if !UCONFIG_NO_TRANSLITERATION
 #if !UCONFIG_NO_IDNA
 
 #include "nptrans.h"
@@ -277,3 +278,4 @@ UBool NamePrepTransform::isLabelSeparator(UChar32 ch, UErrorCode& status){
 }
 
 #endif /* #if !UCONFIG_NO_IDNA */
+#endif /* #if !UCONFIG_NO_TRANSLITERATION */
diff --git a/icu4c/source/test/intltest/nptrans.h b/icu4c/source/test/intltest/nptrans.h
index 06b45db12bb..007a7ef894b 100644
--- a/icu4c/source/test/intltest/nptrans.h
+++ b/icu4c/source/test/intltest/nptrans.h
@@ -20,6 +20,7 @@
 #include "unicode/utypes.h"
 
 #if !UCONFIG_NO_IDNA
+#if !UCONFIG_NO_TRANSLITERATION
 
 #include "strprep.h"
 #include "unicode/uniset.h"
@@ -145,6 +146,10 @@ inline UBool NamePrepTransform::isLDHChar(UChar32 ch){
     return FALSE;
 }
 
+#endif /* #if !UCONFIG_NO_TRANSLITERATION */
+#else
+class NamePrepTransform {
+};
 #endif /* #if !UCONFIG_NO_IDNA */
 
 #endif
diff --git a/icu4c/source/test/intltest/testidn.cpp b/icu4c/source/test/intltest/testidn.cpp
index 74559033315..698aa1adfdc 100644
--- a/icu4c/source/test/intltest/testidn.cpp
+++ b/icu4c/source/test/intltest/testidn.cpp
@@ -23,7 +23,7 @@
 #include <stdlib.h>
 #include "unicode/utypes.h"
 
-#if !UCONFIG_NO_IDNA
+#if !UCONFIG_NO_IDNA && !UCONFIG_NO_TRANSLITERATION
 
 #include "unicode/uchar.h"
 #include "unicode/putil.h"
diff --git a/icu4c/source/test/intltest/testidna.cpp b/icu4c/source/test/intltest/testidna.cpp
index 4921180fb44..5fb5c823531 100644
--- a/icu4c/source/test/intltest/testidna.cpp
+++ b/icu4c/source/test/intltest/testidna.cpp
@@ -16,7 +16,7 @@
 
 #include "unicode/utypes.h"
 
-#if !UCONFIG_NO_IDNA
+#if !UCONFIG_NO_IDNA && !UCONFIG_NO_TRANSLITERATION
 
 #include "unicode/uidna.h"
 #include <time.h>
diff --git a/icu4c/source/test/intltest/testidna.h b/icu4c/source/test/intltest/testidna.h
index 1e7f55b7f9e..3bfe80706d7 100644
--- a/icu4c/source/test/intltest/testidna.h
+++ b/icu4c/source/test/intltest/testidna.h
@@ -19,7 +19,7 @@
 
 #include "unicode/utypes.h"
 
-#if !UCONFIG_NO_IDNA
+#if !UCONFIG_NO_IDNA && !UCONFIG_NO_TRANSLITERATION
 
 #include "sprpimpl.h"
 #include "intltest.h"
@@ -64,7 +64,6 @@ public:
     void TestRefIDNA();
     void TestIDNAMonkeyTest();
     void TestConformance();
-
     static NamePrepTransform* getInstance(UErrorCode& status);
     static NamePrepTransform* prep;
 private: