diff --git a/icu4c/source/i18n/measure.cpp b/icu4c/source/i18n/measure.cpp
index bffa44215e3..23adba10070 100644
--- a/icu4c/source/i18n/measure.cpp
+++ b/icu4c/source/i18n/measure.cpp
@@ -23,7 +23,7 @@ U_NAMESPACE_BEGIN
 
 UOBJECT_DEFINE_RTTI_IMPLEMENTATION(Measure)
 
-Measure::Measure() {}
+Measure::Measure() : unit(nullptr) {}
 
 Measure::Measure(const Formattable& _number, MeasureUnit* adoptedUnit,
                  UErrorCode& ec) :
@@ -35,7 +35,7 @@ Measure::Measure(const Formattable& _number, MeasureUnit* adoptedUnit,
 }
 
 Measure::Measure(const Measure& other) :
-    UObject(other), unit(0) {
+    UObject(other), unit(nullptr) {
     *this = other;
 }
 
@@ -43,7 +43,11 @@ Measure& Measure::operator=(const Measure& other) {
     if (this != &other) {
         delete unit;
         number = other.number;
-        unit = other.unit->clone();
+        if (other.unit != nullptr) {
+            unit = other.unit->clone();
+        } else {
+            unit = nullptr;
+        }
     }
     return *this;
 }
diff --git a/icu4c/source/i18n/number_formatimpl.cpp b/icu4c/source/i18n/number_formatimpl.cpp
index 5bba09cfb52..d5c3e6e4323 100644
--- a/icu4c/source/i18n/number_formatimpl.cpp
+++ b/icu4c/source/i18n/number_formatimpl.cpp
@@ -417,6 +417,7 @@ NumberFormatterImpl::resolvePluralRules(const PluralRules* rulesPtr, const Local
 
 int32_t NumberFormatterImpl::writeAffixes(const MicroProps& micros, FormattedStringBuilder& string,
                                           int32_t start, int32_t end, UErrorCode& status) {
+    U_ASSERT(micros.modOuter != nullptr);
     // Always apply the inner modifier (which is "strong").
     int32_t length = micros.modInner->apply(string, start, end, status);
     if (micros.padding.isValid()) {