diff --git a/icu4c/source/data/brkitr/root.txt b/icu4c/source/data/brkitr/root.txt
index f5b62b8c46b..fab9e29de57 100644
--- a/icu4c/source/data/brkitr/root.txt
+++ b/icu4c/source/data/brkitr/root.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 root{
-    Version{"2.1.44.57"}
+    Version{"2.1.49.32"}
     boundaries{
         grapheme:process(dependency){"char.brk"}
         line:process(dependency){"line.brk"}
diff --git a/icu4c/source/data/curr/ar_AE.txt b/icu4c/source/data/curr/ar_AE.txt
index 3871726203b..a501f5533b5 100644
--- a/icu4c/source/data/curr/ar_AE.txt
+++ b/icu4c/source/data/curr/ar_AE.txt
@@ -4,5 +4,5 @@ ar_AE{
     Currencies%narrow{
         BND{"$"}
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/curr/ceb.txt b/icu4c/source/data/curr/ceb.txt
index ab608d52913..2d932517171 100644
--- a/icu4c/source/data/curr/ceb.txt
+++ b/icu4c/source/data/curr/ceb.txt
@@ -91,5 +91,5 @@ ceb{
         one{"{1} {0}"}
         other{"{1} {0}"}
     }
-    Version{"2.1.48.67"}
+    Version{"2.1.49.33"}
 }
diff --git a/icu4c/source/data/curr/el.txt b/icu4c/source/data/curr/el.txt
index e7f003ce778..91509ad225e 100644
--- a/icu4c/source/data/curr/el.txt
+++ b/icu4c/source/data/curr/el.txt
@@ -2266,5 +2266,5 @@ el{
         one{"{0} {1}"}
         other{"{0} {1}"}
     }
-    Version{"2.1.48.27"}
+    Version{"2.1.49.26"}
 }
diff --git a/icu4c/source/data/curr/en_IN.txt b/icu4c/source/data/curr/en_IN.txt
index 3dc80926069..e8d100beb17 100644
--- a/icu4c/source/data/curr/en_IN.txt
+++ b/icu4c/source/data/curr/en_IN.txt
@@ -22,5 +22,5 @@ en_IN{
             other{"VES"}
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.14"}
 }
diff --git a/icu4c/source/data/curr/eo.txt b/icu4c/source/data/curr/eo.txt
index f84c0c1623c..420b16b3345 100644
--- a/icu4c/source/data/curr/eo.txt
+++ b/icu4c/source/data/curr/eo.txt
@@ -1,5 +1,5 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 eo{
-    Version{"2.1.47.82"}
+    Version{"2.1.49.33"}
 }
diff --git a/icu4c/source/data/curr/ff_Latn_GH.txt b/icu4c/source/data/curr/ff_Latn_GH.txt
index 8e86142eb3f..1d2bf2c5877 100644
--- a/icu4c/source/data/curr/ff_Latn_GH.txt
+++ b/icu4c/source/data/curr/ff_Latn_GH.txt
@@ -7,5 +7,5 @@ ff_Latn_GH{
             "GHS",
         }
     }
-    Version{"2.1.47.82"}
+    Version{"2.1.49.34"}
 }
diff --git a/icu4c/source/data/curr/ff_Latn_GM.txt b/icu4c/source/data/curr/ff_Latn_GM.txt
index 4ea917ace23..d5c370079a1 100644
--- a/icu4c/source/data/curr/ff_Latn_GM.txt
+++ b/icu4c/source/data/curr/ff_Latn_GM.txt
@@ -7,5 +7,5 @@ ff_Latn_GM{
             "Dalasi Gammbi",
         }
     }
-    Version{"2.1.47.82"}
+    Version{"2.1.49.34"}
 }
diff --git a/icu4c/source/data/curr/ff_Latn_LR.txt b/icu4c/source/data/curr/ff_Latn_LR.txt
index 61a1bb10d9b..43153e1dac6 100644
--- a/icu4c/source/data/curr/ff_Latn_LR.txt
+++ b/icu4c/source/data/curr/ff_Latn_LR.txt
@@ -7,5 +7,5 @@ ff_Latn_LR{
             "Dolaar Liberiyaa",
         }
     }
-    Version{"2.1.47.82"}
+    Version{"2.1.49.34"}
 }
diff --git a/icu4c/source/data/curr/ff_Latn_SL.txt b/icu4c/source/data/curr/ff_Latn_SL.txt
index 49af2ce7353..d6aba254958 100644
--- a/icu4c/source/data/curr/ff_Latn_SL.txt
+++ b/icu4c/source/data/curr/ff_Latn_SL.txt
@@ -7,5 +7,5 @@ ff_Latn_SL{
             "Lewoon Seraa Liyon",
         }
     }
-    Version{"2.1.47.82"}
+    Version{"2.1.49.34"}
 }
diff --git a/icu4c/source/data/curr/ms.txt b/icu4c/source/data/curr/ms.txt
index 466153553c3..8b383618a7a 100644
--- a/icu4c/source/data/curr/ms.txt
+++ b/icu4c/source/data/curr/ms.txt
@@ -1248,5 +1248,5 @@ ms{
     CurrencyUnitPatterns{
         other{"{0} {1}"}
     }
-    Version{"2.1.48.42"}
+    Version{"2.1.49.2"}
 }
diff --git a/icu4c/source/data/curr/ps_PK.txt b/icu4c/source/data/curr/ps_PK.txt
index abf069fc50e..833345d5ad3 100644
--- a/icu4c/source/data/curr/ps_PK.txt
+++ b/icu4c/source/data/curr/ps_PK.txt
@@ -21,5 +21,5 @@ ps_PK{
             other{"(نامعلومه مروجه پېسے)"}
         }
     }
-    Version{"2.1.48.67"}
+    Version{"2.1.49.34"}
 }
diff --git a/icu4c/source/data/lang/ar_EG.txt b/icu4c/source/data/lang/ar_EG.txt
index c34d67f27f2..8b2af03965b 100644
--- a/icu4c/source/data/lang/ar_EG.txt
+++ b/icu4c/source/data/lang/ar_EG.txt
@@ -4,5 +4,5 @@ ar_EG{
     Languages{
         da{"الدنماركية"}
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/lang/ar_SA.txt b/icu4c/source/data/lang/ar_SA.txt
index 87af570217f..1d8114504d3 100644
--- a/icu4c/source/data/lang/ar_SA.txt
+++ b/icu4c/source/data/lang/ar_SA.txt
@@ -13,5 +13,5 @@ ar_SA{
         te{"التيلوجو"}
         ti{"التيغرينية"}
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/lang/ceb.txt b/icu4c/source/data/lang/ceb.txt
index bce692d37c9..2442c1edf83 100644
--- a/icu4c/source/data/lang/ceb.txt
+++ b/icu4c/source/data/lang/ceb.txt
@@ -57,7 +57,7 @@ ceb{
             latn{"Kasadpanhong mga Digit"}
         }
     }
-    Version{"2.1.48.67"}
+    Version{"2.1.49.33"}
     codePatterns{
         language{"Pinulongan: {0}"}
         script{"Alpabeto {0}"}
diff --git a/icu4c/source/data/lang/el.txt b/icu4c/source/data/lang/el.txt
index 4a3456b4e15..f44554bd06b 100644
--- a/icu4c/source/data/lang/el.txt
+++ b/icu4c/source/data/lang/el.txt
@@ -328,7 +328,7 @@ el{
         mi{"Μαορί"}
         mic{"Μικμάκ"}
         min{"Μινανγκαμπάου"}
-        mk{"Σλαβομακεδονικά"}
+        mk{"Μακεδονικά"}
         ml{"Μαλαγιαλαμικά"}
         mn{"Μογγολικά"}
         mnc{"Μαντσού"}
@@ -883,7 +883,7 @@ el{
         VALENCIA{"Βαλενθιανά"}
         WADEGILE{"Εκλατινισμένα Γουάντ-Γκιλς"}
     }
-    Version{"2.1.48.27"}
+    Version{"2.1.49.26"}
     characterLabelPattern{
         all{"{0} — όλα"}
         category-list{"{0}: {1}"}
diff --git a/icu4c/source/data/lang/en_IN.txt b/icu4c/source/data/lang/en_IN.txt
index 96984fa8b6d..6e2c60fdfe7 100644
--- a/icu4c/source/data/lang/en_IN.txt
+++ b/icu4c/source/data/lang/en_IN.txt
@@ -15,5 +15,5 @@ en_IN{
             orya{"Oriya Digits"}
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.14"}
 }
diff --git a/icu4c/source/data/lang/eo.txt b/icu4c/source/data/lang/eo.txt
index f1c1c627be4..f20a5d50641 100644
--- a/icu4c/source/data/lang/eo.txt
+++ b/icu4c/source/data/lang/eo.txt
@@ -156,5 +156,5 @@ eo{
         zu{"zulua"}
         zxx{"nelingvaĵo"}
     }
-    Version{"2.1.47.82"}
+    Version{"2.1.49.33"}
 }
diff --git a/icu4c/source/data/lang/ms.txt b/icu4c/source/data/lang/ms.txt
index 3820f261d8f..7e4318177a2 100644
--- a/icu4c/source/data/lang/ms.txt
+++ b/icu4c/source/data/lang/ms.txt
@@ -714,8 +714,9 @@ ms{
     }
     Variants{
         POSIX{"Komputer"}
+        SCOTLAND{"Inggeris Standard Scotland"}
     }
-    Version{"2.1.48.42"}
+    Version{"2.1.49.2"}
     characterLabelPattern{
         all{"{0} — Semua"}
         category-list{"{0}: {1}"}
diff --git a/icu4c/source/data/lang/ps_PK.txt b/icu4c/source/data/lang/ps_PK.txt
index 16545bf1799..da25908ad3d 100644
--- a/icu4c/source/data/lang/ps_PK.txt
+++ b/icu4c/source/data/lang/ps_PK.txt
@@ -16,5 +16,5 @@ ps_PK{
             arabext{"غځېدلے عربي ۔ اينډيک عدد"}
         }
     }
-    Version{"2.1.48.67"}
+    Version{"2.1.49.34"}
 }
diff --git a/icu4c/source/data/locales/ar_AE.txt b/icu4c/source/data/locales/ar_AE.txt
index e2a2419916d..2cbfedd54c0 100644
--- a/icu4c/source/data/locales/ar_AE.txt
+++ b/icu4c/source/data/locales/ar_AE.txt
@@ -8,6 +8,7 @@ ar_AE{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,7 +16,7 @@ ar_AE{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
     calendar{
         gregorian{
             eras{
diff --git a/icu4c/source/data/locales/ar_BH.txt b/icu4c/source/data/locales/ar_BH.txt
index 5f2df59b730..51851b57e5c 100644
--- a/icu4c/source/data/locales/ar_BH.txt
+++ b/icu4c/source/data/locales/ar_BH.txt
@@ -8,6 +8,7 @@ ar_BH{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,5 +16,5 @@ ar_BH{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/locales/ar_EG.txt b/icu4c/source/data/locales/ar_EG.txt
index 2c78ec2b8fa..02a9af005eb 100644
--- a/icu4c/source/data/locales/ar_EG.txt
+++ b/icu4c/source/data/locales/ar_EG.txt
@@ -8,6 +8,7 @@ ar_EG{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,5 +16,5 @@ ar_EG{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/locales/ar_IQ.txt b/icu4c/source/data/locales/ar_IQ.txt
index 20c06c49ab6..0ca4f834e10 100644
--- a/icu4c/source/data/locales/ar_IQ.txt
+++ b/icu4c/source/data/locales/ar_IQ.txt
@@ -8,6 +8,7 @@ ar_IQ{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,7 +16,7 @@ ar_IQ{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
     calendar{
         gregorian{
             monthNames{
diff --git a/icu4c/source/data/locales/ar_JO.txt b/icu4c/source/data/locales/ar_JO.txt
index 26a567f1127..4ee13ad14b1 100644
--- a/icu4c/source/data/locales/ar_JO.txt
+++ b/icu4c/source/data/locales/ar_JO.txt
@@ -8,6 +8,7 @@ ar_JO{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,7 +16,7 @@ ar_JO{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
     calendar{
         gregorian{
             monthNames{
diff --git a/icu4c/source/data/locales/ar_KW.txt b/icu4c/source/data/locales/ar_KW.txt
index 64fe9154be5..069dc23de45 100644
--- a/icu4c/source/data/locales/ar_KW.txt
+++ b/icu4c/source/data/locales/ar_KW.txt
@@ -8,6 +8,7 @@ ar_KW{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,5 +16,5 @@ ar_KW{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/locales/ar_OM.txt b/icu4c/source/data/locales/ar_OM.txt
index d796b4b55a7..bdfd2ed3f90 100644
--- a/icu4c/source/data/locales/ar_OM.txt
+++ b/icu4c/source/data/locales/ar_OM.txt
@@ -8,6 +8,7 @@ ar_OM{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,5 +16,5 @@ ar_OM{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/locales/ar_QA.txt b/icu4c/source/data/locales/ar_QA.txt
index b56404ed89f..4d37c59147d 100644
--- a/icu4c/source/data/locales/ar_QA.txt
+++ b/icu4c/source/data/locales/ar_QA.txt
@@ -8,6 +8,7 @@ ar_QA{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,5 +16,5 @@ ar_QA{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/locales/ar_SA.txt b/icu4c/source/data/locales/ar_SA.txt
index 7b23c8fbcb2..1dcdf3cf23f 100644
--- a/icu4c/source/data/locales/ar_SA.txt
+++ b/icu4c/source/data/locales/ar_SA.txt
@@ -3,13 +3,14 @@
 ar_SA{
     ExemplarCharactersNumbers{"[\u200E \\- , . ٪ ‰ + 0 1 2 3 4 5 6 7 8 9]"}
     NumberElements{
+        default{"arab"}
         latn{
             symbols{
                 percentSign{"٪"}
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
     calendar{
         default{"islamic-umalqura"}
         gregorian{
diff --git a/icu4c/source/data/locales/ar_SD.txt b/icu4c/source/data/locales/ar_SD.txt
index a6507b55af2..2a3cd96dc0c 100644
--- a/icu4c/source/data/locales/ar_SD.txt
+++ b/icu4c/source/data/locales/ar_SD.txt
@@ -8,6 +8,7 @@ ar_SD{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,5 +16,5 @@ ar_SD{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/locales/ar_SY.txt b/icu4c/source/data/locales/ar_SY.txt
index e834fc9dc5a..4fdfb81f1d8 100644
--- a/icu4c/source/data/locales/ar_SY.txt
+++ b/icu4c/source/data/locales/ar_SY.txt
@@ -8,6 +8,7 @@ ar_SY{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,7 +16,7 @@ ar_SY{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
     calendar{
         gregorian{
             monthNames{
diff --git a/icu4c/source/data/locales/ar_YE.txt b/icu4c/source/data/locales/ar_YE.txt
index fab8c2f6f6f..ae46ec4f891 100644
--- a/icu4c/source/data/locales/ar_YE.txt
+++ b/icu4c/source/data/locales/ar_YE.txt
@@ -8,6 +8,7 @@ ar_YE{
                 group{"٬"}
             }
         }
+        default{"arab"}
         latn{
             symbols{
                 decimal{"."}
@@ -15,5 +16,5 @@ ar_YE{
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/locales/ceb.txt b/icu4c/source/data/locales/ceb.txt
index 77a345774b2..a47feac765c 100644
--- a/icu4c/source/data/locales/ceb.txt
+++ b/icu4c/source/data/locales/ceb.txt
@@ -22,7 +22,7 @@ ceb{
             }
         }
     }
-    Version{"2.1.48.67"}
+    Version{"2.1.49.33"}
     calendar{
         generic{
             DateTimePatterns{
diff --git a/icu4c/source/data/locales/el.txt b/icu4c/source/data/locales/el.txt
index fd118a08a18..e721218cef1 100644
--- a/icu4c/source/data/locales/el.txt
+++ b/icu4c/source/data/locales/el.txt
@@ -211,7 +211,7 @@ el{
         minimumGroupingDigits{"1"}
         traditional{"grek"}
     }
-    Version{"2.1.48.27"}
+    Version{"2.1.49.26"}
     calendar{
         buddhist{
             DateTimePatterns{
diff --git a/icu4c/source/data/locales/en_IN.txt b/icu4c/source/data/locales/en_IN.txt
index ec47487f9c1..0a31a0cb503 100644
--- a/icu4c/source/data/locales/en_IN.txt
+++ b/icu4c/source/data/locales/en_IN.txt
@@ -23,6 +23,10 @@ en_IN{
                         one{"¤0L"}
                         other{"¤0L"}
                     }
+                    1000000{
+                        one{"¤00L"}
+                        other{"¤00L"}
+                    }
                     10000000{
                         one{"¤0Cr"}
                         other{"¤0Cr"}
@@ -31,6 +35,10 @@ en_IN{
                         one{"¤00Cr"}
                         other{"¤00Cr"}
                     }
+                    1000000000{
+                        one{"¤000Cr"}
+                        other{"¤000Cr"}
+                    }
                     10000000000{
                         one{"¤0TCr"}
                         other{"¤0TCr"}
@@ -39,11 +47,23 @@ en_IN{
                         one{"¤00TCr"}
                         other{"¤00TCr"}
                     }
+                    1000000000000{
+                        one{"¤0LCr"}
+                        other{"¤0LCr"}
+                    }
+                    10000000000000{
+                        one{"¤00LCr"}
+                        other{"¤00LCr"}
+                    }
+                    100000000000000{
+                        one{"¤000LCr"}
+                        other{"¤000LCr"}
+                    }
                 }
             }
         }
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.14"}
     calendar{
         generic{
             DateTimePatterns{
diff --git a/icu4c/source/data/locales/eo.txt b/icu4c/source/data/locales/eo.txt
index 70d80b7d70f..9f44cb74e1a 100644
--- a/icu4c/source/data/locales/eo.txt
+++ b/icu4c/source/data/locales/eo.txt
@@ -14,7 +14,7 @@ eo{
             }
         }
     }
-    Version{"2.1.47.82"}
+    Version{"2.1.49.33"}
     calendar{
         generic{
             DateTimePatterns{
diff --git a/icu4c/source/data/locales/ff_Latn_GH.txt b/icu4c/source/data/locales/ff_Latn_GH.txt
index f9203c29afd..d2e389d3ab9 100644
--- a/icu4c/source/data/locales/ff_Latn_GH.txt
+++ b/icu4c/source/data/locales/ff_Latn_GH.txt
@@ -1,5 +1,24 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ff_Latn_GH{
-    Version{"2.1.47.82"}
+    Version{"2.1.49.34"}
+    calendar{
+        gregorian{
+            DateTimePatterns{
+                "h:mm:ss a zzzz",
+                "h:mm:ss a z",
+                "h:mm:ss a",
+                "h:mm a",
+                "EEEE d MMMM y",
+                "d MMMM y",
+                "d MMM, y",
+                "d/M/y",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+            }
+        }
+    }
 }
diff --git a/icu4c/source/data/locales/ff_Latn_GM.txt b/icu4c/source/data/locales/ff_Latn_GM.txt
index 4768edf4caa..1d129f77a98 100644
--- a/icu4c/source/data/locales/ff_Latn_GM.txt
+++ b/icu4c/source/data/locales/ff_Latn_GM.txt
@@ -1,5 +1,24 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ff_Latn_GM{
-    Version{"2.1.47.82"}
+    Version{"2.1.49.34"}
+    calendar{
+        gregorian{
+            DateTimePatterns{
+                "h:mm:ss a zzzz",
+                "h:mm:ss a z",
+                "h:mm:ss a",
+                "h:mm a",
+                "EEEE d MMMM y",
+                "d MMMM y",
+                "d MMM, y",
+                "d/M/y",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+            }
+        }
+    }
 }
diff --git a/icu4c/source/data/locales/ff_Latn_LR.txt b/icu4c/source/data/locales/ff_Latn_LR.txt
index dcb8f354327..30c13dce550 100644
--- a/icu4c/source/data/locales/ff_Latn_LR.txt
+++ b/icu4c/source/data/locales/ff_Latn_LR.txt
@@ -1,5 +1,24 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ff_Latn_LR{
-    Version{"2.1.47.82"}
+    Version{"2.1.49.34"}
+    calendar{
+        gregorian{
+            DateTimePatterns{
+                "h:mm:ss a zzzz",
+                "h:mm:ss a z",
+                "h:mm:ss a",
+                "h:mm a",
+                "EEEE d MMMM y",
+                "d MMMM y",
+                "d MMM, y",
+                "d/M/y",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+            }
+        }
+    }
 }
diff --git a/icu4c/source/data/locales/ff_Latn_SL.txt b/icu4c/source/data/locales/ff_Latn_SL.txt
index d6e82513cc4..adadacdc709 100644
--- a/icu4c/source/data/locales/ff_Latn_SL.txt
+++ b/icu4c/source/data/locales/ff_Latn_SL.txt
@@ -1,5 +1,24 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ff_Latn_SL{
-    Version{"2.1.47.82"}
+    Version{"2.1.49.34"}
+    calendar{
+        gregorian{
+            DateTimePatterns{
+                "h:mm:ss a zzzz",
+                "h:mm:ss a z",
+                "h:mm:ss a",
+                "h:mm a",
+                "EEEE d MMMM y",
+                "d MMMM y",
+                "d MMM, y",
+                "d/M/y",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+            }
+        }
+    }
 }
diff --git a/icu4c/source/data/locales/ms.txt b/icu4c/source/data/locales/ms.txt
index ff720c47495..379acf419c3 100644
--- a/icu4c/source/data/locales/ms.txt
+++ b/icu4c/source/data/locales/ms.txt
@@ -174,7 +174,7 @@ ms{
         minimumGroupingDigits{"1"}
         native{"latn"}
     }
-    Version{"2.1.48.42"}
+    Version{"2.1.49.2"}
     calendar{
         chinese{
             DateTimePatterns{
diff --git a/icu4c/source/data/locales/ps_PK.txt b/icu4c/source/data/locales/ps_PK.txt
index 872b6c02bc9..dc52558ba02 100644
--- a/icu4c/source/data/locales/ps_PK.txt
+++ b/icu4c/source/data/locales/ps_PK.txt
@@ -7,8 +7,25 @@ ps_PK{
         " ء ب پ ت ټ ث ج ځ چ څ ح خ د ډ ذ ر ړ ز ژ ږ س ش ښ ص ض ط ظ ع غ ف ق ک ګ گ ل م ن ڼ"
         " ه ة و ؤ ی ے ي ې ۍ ئ]"
     }
-    Version{"2.1.48.67"}
+    Version{"2.1.49.34"}
     calendar{
+        gregorian{
+            DateTimePatterns{
+                "h:mm:ss a zzzz",
+                "h:mm:ss a z",
+                "h:mm:ss a",
+                "h:mm a",
+                "EEEE د y د MMMM d",
+                "د y د MMMM d",
+                "y MMM d",
+                "y/M/d",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+                "{1} {0}",
+            }
+        }
         islamic{
             monthNames{
                 format{
diff --git a/icu4c/source/data/misc/metadata.txt b/icu4c/source/data/misc/metadata.txt
index bd584abf2ad..239591cd391 100644
--- a/icu4c/source/data/misc/metadata.txt
+++ b/icu4c/source/data/misc/metadata.txt
@@ -195,6 +195,10 @@ metadata:table(nofallback){
                 reason{"deprecated"}
                 replacement{"rki"}
             }
+            cel-gaulish{
+                reason{"legacy"}
+                replacement{"xtg-x-cel-gaulish"}
+            }
             ces{
                 reason{"overlong"}
                 replacement{"cs"}
@@ -539,6 +543,18 @@ metadata:table(nofallback){
                 reason{"overlong"}
                 replacement{"hy"}
             }
+            i-default{
+                reason{"legacy"}
+                replacement{"en-x-i-default"}
+            }
+            i-enochian{
+                reason{"legacy"}
+                replacement{"und-x-i-enochian"}
+            }
+            i-mingo{
+                reason{"legacy"}
+                replacement{"see-x-i-mingo"}
+            }
             i_ami{
                 reason{"deprecated"}
                 replacement{"ami"}
@@ -1587,6 +1603,10 @@ metadata:table(nofallback){
                 reason{"macrolanguage"}
                 replacement{"zap"}
             }
+            zh-min{
+                reason{"legacy"}
+                replacement{"nan-x-zh-min"}
+            }
             zh_CN{
                 reason{"legacy"}
                 replacement{"zh_Hans_CN"}
@@ -1669,7 +1689,7 @@ metadata:table(nofallback){
             }
             cn15{
                 reason{"deprecated"}
-                replacement{"cnnm"}
+                replacement{"cnmn"}
             }
             cn21{
                 reason{"deprecated"}
@@ -1811,6 +1831,10 @@ metadata:table(nofallback){
                 reason{"deprecated"}
                 replacement{"cz115"}
             }
+            cz611{
+                reason{"deprecated"}
+                replacement{"cz663"}
+            }
             cz612{
                 reason{"deprecated"}
                 replacement{"cz632"}
@@ -2103,6 +2127,70 @@ metadata:table(nofallback){
                 reason{"deprecated"}
                 replacement{"omsj omss"}
             }
+            plds{
+                reason{"deprecated"}
+                replacement{"pl02"}
+            }
+            plkp{
+                reason{"deprecated"}
+                replacement{"pl04"}
+            }
+            pllb{
+                reason{"deprecated"}
+                replacement{"pl08"}
+            }
+            plld{
+                reason{"deprecated"}
+                replacement{"pl10"}
+            }
+            pllu{
+                reason{"deprecated"}
+                replacement{"pl06"}
+            }
+            plma{
+                reason{"deprecated"}
+                replacement{"pl12"}
+            }
+            plmz{
+                reason{"deprecated"}
+                replacement{"pl14"}
+            }
+            plop{
+                reason{"deprecated"}
+                replacement{"pl16"}
+            }
+            plpd{
+                reason{"deprecated"}
+                replacement{"pl20"}
+            }
+            plpk{
+                reason{"deprecated"}
+                replacement{"pl18"}
+            }
+            plpm{
+                reason{"deprecated"}
+                replacement{"pl22"}
+            }
+            plsk{
+                reason{"deprecated"}
+                replacement{"pl26"}
+            }
+            plsl{
+                reason{"deprecated"}
+                replacement{"pl24"}
+            }
+            plwn{
+                reason{"deprecated"}
+                replacement{"pl28"}
+            }
+            plwp{
+                reason{"deprecated"}
+                replacement{"pl30"}
+            }
+            plzp{
+                reason{"deprecated"}
+                replacement{"pl32"}
+            }
             shta{
                 reason{"overlong"}
                 replacement{"TA"}
diff --git a/icu4c/source/data/misc/supplementalData.txt b/icu4c/source/data/misc/supplementalData.txt
index 32b805919e0..1f3d63e28ab 100644
--- a/icu4c/source/data/misc/supplementalData.txt
+++ b/icu4c/source/data/misc/supplementalData.txt
@@ -7899,7 +7899,10 @@ supplementalData:table(nofallback){
                 "cn61~5",
                 "cn71",
                 "cn91~2",
+                "cz101~9",
                 "cz10a~f",
+                "cz110~9",
+                "cz120~2",
                 "cz611~5",
                 "cz621~7",
                 "czjc",
@@ -7965,6 +7968,7 @@ supplementalData:table(nofallback){
                 "gbnym",
                 "gbomh",
                 "gbstb",
+                "glqa",
                 "gr01",
                 "gr03~7",
                 "gr11~7",
@@ -7999,14 +8003,37 @@ supplementalData:table(nofallback){
                 "mk79",
                 "mk84",
                 "mrnkc",
+                "mvce",
+                "mvnc",
+                "mvno",
+                "mvsc",
+                "mvsu",
+                "mvun",
+                "mvus",
                 "mxdif",
                 "nlaw",
                 "nlcw",
                 "nlsx",
+                "no16~7",
                 "nzn",
                 "nzs",
                 "omba",
                 "omsh",
+                "plds",
+                "plkp",
+                "pllb",
+                "plld",
+                "pllu",
+                "plma",
+                "plmz",
+                "plop",
+                "plpd",
+                "plpk",
+                "plpm",
+                "plsk~l",
+                "plwn",
+                "plwp",
+                "plzp",
                 "shta",
                 "tteto",
                 "ttrcm",
@@ -8342,7 +8369,7 @@ supplementalData:table(nofallback){
                 "bsmg",
                 "bsmi",
                 "bsne",
-                "bsno",
+                "bsno~p",
                 "bsns",
                 "bsrc",
                 "bsri",
@@ -8493,6 +8520,7 @@ supplementalData:table(nofallback){
                 "cllr",
                 "clma",
                 "clml",
+                "clnb",
                 "clrm",
                 "clta",
                 "clvs",
@@ -8605,9 +8633,6 @@ supplementalData:table(nofallback){
                 "cvts",
                 "cy01~6",
                 "cz10",
-                "cz101~9",
-                "cz110~9",
-                "cz120~2",
                 "cz20",
                 "cz201~9",
                 "cz20a~c",
@@ -9068,9 +9093,10 @@ supplementalData:table(nofallback){
                 "ghue",
                 "ghuw",
                 "ghwp",
+                "glav",
                 "glku",
-                "glqa",
                 "glqe",
+                "glqt",
                 "glsm",
                 "gmb",
                 "gml~n",
@@ -9522,6 +9548,7 @@ supplementalData:table(nofallback){
                 "kzman",
                 "kzpav",
                 "kzsev",
+                "kzshy",
                 "kzvos",
                 "kzyuz",
                 "kzzap",
@@ -9887,14 +9914,7 @@ supplementalData:table(nofallback){
                 "mv17",
                 "mv20",
                 "mv23~9",
-                "mvce",
                 "mvmle",
-                "mvnc",
-                "mvno",
-                "mvsc",
-                "mvsu",
-                "mvun",
-                "mvus",
                 "mwba",
                 "mwbl",
                 "mwc",
@@ -10046,8 +10066,9 @@ supplementalData:table(nofallback){
                 "nlzh",
                 "no01~9",
                 "no10~2",
-                "no14~9",
-                "no20~2",
+                "no14~5",
+                "no18~9",
+                "no20~3",
                 "np1~5",
                 "npba",
                 "npbh",
@@ -10060,6 +10081,7 @@ supplementalData:table(nofallback){
                 "npma",
                 "npme",
                 "npna",
+                "npp1~7",
                 "npra",
                 "npsa",
                 "npse",
@@ -10234,21 +10256,22 @@ supplementalData:table(nofallback){
                 "pkpb",
                 "pksd",
                 "pkta",
-                "plds",
-                "plkp",
-                "pllb",
-                "plld",
-                "pllu",
-                "plma",
-                "plmz",
-                "plop",
-                "plpd",
-                "plpk",
-                "plpm",
-                "plsk~l",
-                "plwn",
-                "plwp",
-                "plzp",
+                "pl02",
+                "pl04",
+                "pl06",
+                "pl08",
+                "pl10",
+                "pl12",
+                "pl14",
+                "pl16",
+                "pl18",
+                "pl20",
+                "pl22",
+                "pl24",
+                "pl26",
+                "pl28",
+                "pl30",
+                "pl32",
                 "psbth",
                 "psdeb",
                 "psgza",
@@ -10498,6 +10521,7 @@ supplementalData:table(nofallback){
                 "skzi",
                 "sle",
                 "sln",
+                "slnw",
                 "sls",
                 "slw",
                 "sm01~9",
@@ -10711,7 +10735,7 @@ supplementalData:table(nofallback){
                 "tz01~9",
                 "tz10~9",
                 "tz20~9",
-                "tz30",
+                "tz30~1",
                 "ua05",
                 "ua07",
                 "ua09",
@@ -10741,19 +10765,19 @@ supplementalData:table(nofallback){
                 "ua77",
                 "ug101~9",
                 "ug110~9",
-                "ug120~5",
+                "ug120~6",
                 "ug201~9",
                 "ug210~9",
                 "ug220~9",
-                "ug230~4",
+                "ug230~6",
                 "ug301~9",
                 "ug310~9",
                 "ug320~9",
-                "ug330~2",
+                "ug330~4",
                 "ug401~9",
                 "ug410~9",
                 "ug420~9",
-                "ug430~1",
+                "ug430~2",
                 "ugc",
                 "uge",
                 "ugn",
@@ -19802,6 +19826,7 @@ supplementalData:table(nofallback){
             "bsmi",
             "bsne",
             "bsno",
+            "bsnp",
             "bsns",
             "bsrc",
             "bsri",
@@ -20002,6 +20027,7 @@ supplementalData:table(nofallback){
             "cllr",
             "clma",
             "clml",
+            "clnb",
             "clrm",
             "clta",
             "clvs",
@@ -20483,9 +20509,10 @@ supplementalData:table(nofallback){
             "ghwp",
         }
         GL{
+            "glav",
             "glku",
-            "glqa",
             "glqe",
+            "glqt",
             "glsm",
         }
         GM{
@@ -21049,6 +21076,7 @@ supplementalData:table(nofallback){
             "kzman",
             "kzpav",
             "kzsev",
+            "kzshy",
             "kzvos",
             "kzyuz",
             "kzzap",
@@ -21723,14 +21751,27 @@ supplementalData:table(nofallback){
             "muvp",
         }
         MV{
-            "mvce",
+            "mv00",
+            "mv01",
+            "mv02",
+            "mv03",
+            "mv04",
+            "mv05",
+            "mv07",
+            "mv08",
+            "mv12",
+            "mv13",
+            "mv14",
+            "mv17",
+            "mv20",
+            "mv23",
+            "mv24",
+            "mv25",
+            "mv26",
+            "mv27",
+            "mv28",
+            "mv29",
             "mvmle",
-            "mvnc",
-            "mvno",
-            "mvsc",
-            "mvsu",
-            "mvun",
-            "mvus",
         }
         MW{
             "mwc",
@@ -21921,13 +21962,12 @@ supplementalData:table(nofallback){
             "no12",
             "no14",
             "no15",
-            "no16",
-            "no17",
             "no18",
             "no19",
             "no20",
             "no21",
             "no22",
+            "no23",
         }
         NP{
             "np1",
@@ -21935,6 +21975,13 @@ supplementalData:table(nofallback){
             "np3",
             "np4",
             "np5",
+            "npp1",
+            "npp2",
+            "npp3",
+            "npp4",
+            "npp5",
+            "npp6",
+            "npp7",
         }
         NR{
             "nr01",
@@ -22081,22 +22128,22 @@ supplementalData:table(nofallback){
             "pkta",
         }
         PL{
-            "plds",
-            "plkp",
-            "pllb",
-            "plld",
-            "pllu",
-            "plma",
-            "plmz",
-            "plop",
-            "plpd",
-            "plpk",
-            "plpm",
-            "plsk",
-            "plsl",
-            "plwn",
-            "plwp",
-            "plzp",
+            "pl02",
+            "pl04",
+            "pl06",
+            "pl08",
+            "pl10",
+            "pl12",
+            "pl14",
+            "pl16",
+            "pl18",
+            "pl20",
+            "pl22",
+            "pl24",
+            "pl26",
+            "pl28",
+            "pl30",
+            "pl32",
         }
         PS{
             "psbth",
@@ -22680,6 +22727,7 @@ supplementalData:table(nofallback){
         SL{
             "sle",
             "sln",
+            "slnw",
             "sls",
             "slw",
         }
@@ -23136,6 +23184,7 @@ supplementalData:table(nofallback){
             "tz28",
             "tz29",
             "tz30",
+            "tz31",
         }
         UA{
             "ua05",
@@ -23663,30 +23712,6 @@ supplementalData:table(nofallback){
             "cvss",
             "cvta",
         }
-        cz10{
-            "cz101",
-            "cz102",
-            "cz103",
-            "cz104",
-            "cz105",
-            "cz106",
-            "cz107",
-            "cz108",
-            "cz109",
-            "cz110",
-            "cz111",
-            "cz112",
-            "cz113",
-            "cz114",
-            "cz115",
-            "cz116",
-            "cz117",
-            "cz118",
-            "cz119",
-            "cz120",
-            "cz121",
-            "cz122",
-        }
         cz20{
             "cz20a",
             "cz20b",
@@ -24773,40 +24798,6 @@ supplementalData:table(nofallback){
             "mhuti",
             "mhwtj",
         }
-        mvce{
-            "mv12",
-            "mv14",
-            "mv17",
-        }
-        mvnc{
-            "mv00",
-            "mv02",
-            "mv04",
-            "mv26",
-        }
-        mvno{
-            "mv03",
-            "mv13",
-            "mv20",
-            "mv25",
-        }
-        mvsc{
-            "mv27",
-            "mv28",
-        }
-        mvsu{
-            "mv01",
-            "mv29",
-        }
-        mvun{
-            "mv07",
-            "mv23",
-            "mv24",
-        }
-        mvus{
-            "mv05",
-            "mv08",
-        }
         mwc{
             "mwde",
             "mwdo",
@@ -25020,6 +25011,7 @@ supplementalData:table(nofallback){
             "ug123",
             "ug124",
             "ug125",
+            "ug126",
         }
         uge{
             "ug201",
@@ -25056,6 +25048,8 @@ supplementalData:table(nofallback){
             "ug232",
             "ug233",
             "ug234",
+            "ug235",
+            "ug236",
         }
         ugn{
             "ug301",
@@ -25090,6 +25084,8 @@ supplementalData:table(nofallback){
             "ug330",
             "ug331",
             "ug332",
+            "ug333",
+            "ug334",
         }
         ugw{
             "ug401",
@@ -25123,6 +25119,7 @@ supplementalData:table(nofallback){
             "ug429",
             "ug430",
             "ug431",
+            "ug432",
         }
     }
     territoryContainment{
diff --git a/icu4c/source/data/rbnf/ms.txt b/icu4c/source/data/rbnf/ms.txt
index 92707337270..c1832bdd3c4 100644
--- a/icu4c/source/data/rbnf/ms.txt
+++ b/icu4c/source/data/rbnf/ms.txt
@@ -6,6 +6,8 @@ ms{
             "%digits-ordinal:",
             "-x: \u2212ke->#,##0>;",
             "0: ke-=#,##0=;",
+            "1: No. 1;",
+            "2: ke-=#,##0=;",
         }
         SpelloutRules{
             "%spellout-numbering-year:",
@@ -15,7 +17,7 @@ ms{
             "0: =%spellout-cardinal=;",
             "%spellout-cardinal:",
             "-x: negatif >>;",
-            "x.x: << titik >>;",
+            "x.x: << perpuluhan >>;",
             "0: kosong;",
             "1: satu;",
             "2: dua;",
@@ -34,10 +36,11 @@ ms{
             "200: << ratus[ >>];",
             "1000: seribu[ >>];",
             "2000: << ribu[ >>];",
-            "1000000: << juta[ >>];",
-            "1000000000: << milyar[ >>];",
-            "1000000000000: << bilyun[ >>];",
-            "1000000000000000: << bilyar[ >>];",
+            "1000000: sejuta[ >>];",
+            "2000000: << juta[ >>];",
+            "1000000000: << bilion[ >>];",
+            "1000000000000: << trilion[ >>];",
+            "1000000000000000: << kuadrilion[ >>];",
             "1000000000000000000: =#,##0=;",
             "%spellout-ordinal:",
             "-x: negatif >>;",
@@ -47,5 +50,5 @@ ms{
             "2: ke=%spellout-cardinal=;",
         }
     }
-    Version{"2.1.31.40"}
+    Version{"2.1.49.24"}
 }
diff --git a/icu4c/source/data/region/ar_AE.txt b/icu4c/source/data/region/ar_AE.txt
index 27ce60fb2f2..a5360ca1923 100644
--- a/icu4c/source/data/region/ar_AE.txt
+++ b/icu4c/source/data/region/ar_AE.txt
@@ -5,5 +5,5 @@ ar_AE{
         CI{"ساحل العاج"}
         TL{"التيمور الشرقية"}
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/region/ar_SA.txt b/icu4c/source/data/region/ar_SA.txt
index badd2b05c66..8b0b0535880 100644
--- a/icu4c/source/data/region/ar_SA.txt
+++ b/icu4c/source/data/region/ar_SA.txt
@@ -15,5 +15,5 @@ ar_SA{
     Countries%variant{
         CZ{"التشيك"}
     }
-    Version{"2.1.47.86"}
+    Version{"2.1.49.36"}
 }
diff --git a/icu4c/source/data/region/ceb.txt b/icu4c/source/data/region/ceb.txt
index 722bd7940b7..1f838b31164 100644
--- a/icu4c/source/data/region/ceb.txt
+++ b/icu4c/source/data/region/ceb.txt
@@ -10,9 +10,10 @@ ceb{
         IN{"India"}
         IT{"Italya"}
         JP{"Hapon"}
+        PH{"Pilipinas"}
         RU{"Russia"}
         US{"Estados Unidos"}
         ZZ{"Wala-mailhing Rehiyon"}
     }
-    Version{"2.1.48.67"}
+    Version{"2.1.49.33"}
 }
diff --git a/icu4c/source/data/region/el.txt b/icu4c/source/data/region/el.txt
index f814b973cf9..21772b96450 100644
--- a/icu4c/source/data/region/el.txt
+++ b/icu4c/source/data/region/el.txt
@@ -312,5 +312,5 @@ el{
         FK{"Νήσοι Φόκλαντ (Νήσοι Μαλβίνας)"}
         TL{"Ανατολικό Τιμόρ"}
     }
-    Version{"2.1.48.27"}
+    Version{"2.1.49.26"}
 }
diff --git a/icu4c/source/data/region/en_IN.txt b/icu4c/source/data/region/en_IN.txt
index ebf99c2ceb1..afae6a989f1 100644
--- a/icu4c/source/data/region/en_IN.txt
+++ b/icu4c/source/data/region/en_IN.txt
@@ -2,5 +2,5 @@
 // License & terms of use: http://www.unicode.org/copyright.html#License
 en_IN{
     %%Parent{"en_001"}
-    Version{"2.1.47.86"}
+    Version{"2.1.49.14"}
 }
diff --git a/icu4c/source/data/region/eo.txt b/icu4c/source/data/region/eo.txt
index 195696a340f..18f2955dc1a 100644
--- a/icu4c/source/data/region/eo.txt
+++ b/icu4c/source/data/region/eo.txt
@@ -2,6 +2,7 @@
 // License & terms of use: http://www.unicode.org/copyright.html#License
 eo{
     Countries{
+        001{"Mondo"}
         AD{"Andoro"}
         AE{"Unuiĝintaj Arabaj Emirlandoj"}
         AF{"Afganujo"}
@@ -226,5 +227,5 @@ eo{
         ZM{"Zambio"}
         ZW{"Zimbabvo"}
     }
-    Version{"2.1.47.82"}
+    Version{"2.1.49.33"}
 }
diff --git a/icu4c/source/data/region/ms.txt b/icu4c/source/data/region/ms.txt
index b835f97bec8..d7995916fcd 100644
--- a/icu4c/source/data/region/ms.txt
+++ b/icu4c/source/data/region/ms.txt
@@ -313,5 +313,5 @@ ms{
         FK{"Kepulauan Falkland (Islas Malvinas)"}
         TL{"Timor Timur"}
     }
-    Version{"2.1.48.42"}
+    Version{"2.1.49.2"}
 }
diff --git a/icu4c/source/data/region/ps_PK.txt b/icu4c/source/data/region/ps_PK.txt
index b1055c61b4c..13bc1e3f94c 100644
--- a/icu4c/source/data/region/ps_PK.txt
+++ b/icu4c/source/data/region/ps_PK.txt
@@ -7,5 +7,5 @@ ps_PK{
         TC{"د ترکیے او کیکاسو ټاپو"}
         TF{"د فرانسے جنوبي سیمے"}
     }
-    Version{"2.1.48.67"}
+    Version{"2.1.49.34"}
 }
diff --git a/icu4c/source/data/unit/ceb.txt b/icu4c/source/data/unit/ceb.txt
index b895231d829..c8985917b51 100644
--- a/icu4c/source/data/unit/ceb.txt
+++ b/icu4c/source/data/unit/ceb.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ceb{
-    Version{"2.1.48.67"}
+    Version{"2.1.49.33"}
     durationUnits{
         hm{"h:mm"}
         hms{"h:mm:ss"}
diff --git a/icu4c/source/data/unit/el.txt b/icu4c/source/data/unit/el.txt
index a3a66457720..71f44475474 100644
--- a/icu4c/source/data/unit/el.txt
+++ b/icu4c/source/data/unit/el.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 el{
-    Version{"2.1.48.27"}
+    Version{"2.1.49.26"}
     durationUnits{
         hm{"h:mm"}
         hms{"h:mm:ss"}
diff --git a/icu4c/source/data/unit/en_IN.txt b/icu4c/source/data/unit/en_IN.txt
index d5c93b3538c..e7a08903785 100644
--- a/icu4c/source/data/unit/en_IN.txt
+++ b/icu4c/source/data/unit/en_IN.txt
@@ -2,7 +2,7 @@
 // License & terms of use: http://www.unicode.org/copyright.html#License
 en_IN{
     %%Parent{"en_001"}
-    Version{"2.1.47.86"}
+    Version{"2.1.49.14"}
     unitsNarrow{
         speed{
             kilometer-per-hour{
diff --git a/icu4c/source/data/unit/eo.txt b/icu4c/source/data/unit/eo.txt
index 1f7a4409fe4..3748c6cffe5 100644
--- a/icu4c/source/data/unit/eo.txt
+++ b/icu4c/source/data/unit/eo.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 eo{
-    Version{"2.1.47.82"}
+    Version{"2.1.49.33"}
     unitsShort{
         duration{
             month{
diff --git a/icu4c/source/data/unit/ms.txt b/icu4c/source/data/unit/ms.txt
index e03194afd5e..e55b3ed8c6c 100644
--- a/icu4c/source/data/unit/ms.txt
+++ b/icu4c/source/data/unit/ms.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ms{
-    Version{"2.1.48.42"}
+    Version{"2.1.49.2"}
     durationUnits{
         hm{"h:mm"}
         hms{"h:mm:ss"}
diff --git a/icu4c/source/data/unit/ps_PK.txt b/icu4c/source/data/unit/ps_PK.txt
index da331f79180..399590a0081 100644
--- a/icu4c/source/data/unit/ps_PK.txt
+++ b/icu4c/source/data/unit/ps_PK.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ps_PK{
-    Version{"2.1.48.67"}
+    Version{"2.1.49.34"}
     units{
         acceleration{
             g-force{
diff --git a/icu4c/source/data/zone/ceb.txt b/icu4c/source/data/zone/ceb.txt
index 21eec4d450e..6dd74c1ca66 100644
--- a/icu4c/source/data/zone/ceb.txt
+++ b/icu4c/source/data/zone/ceb.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ceb{
-    Version{"2.1.48.67"}
+    Version{"2.1.49.33"}
     zoneStrings{
         "Etc:UTC"{
             ls{"Koordinado nga Unibersohanong Oras"}
diff --git a/icu4c/source/data/zone/el.txt b/icu4c/source/data/zone/el.txt
index b5230e0ce3f..aa438507dcb 100644
--- a/icu4c/source/data/zone/el.txt
+++ b/icu4c/source/data/zone/el.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 el{
-    Version{"2.1.48.27"}
+    Version{"2.1.49.26"}
     zoneStrings{
         "Africa:Abidjan"{
             ec{"Αμπιτζάν"}
diff --git a/icu4c/source/data/zone/en_IN.txt b/icu4c/source/data/zone/en_IN.txt
index ff5dc3c086d..78072b11aa1 100644
--- a/icu4c/source/data/zone/en_IN.txt
+++ b/icu4c/source/data/zone/en_IN.txt
@@ -2,7 +2,7 @@
 // License & terms of use: http://www.unicode.org/copyright.html#License
 en_IN{
     %%Parent{"en_001"}
-    Version{"2.1.47.86"}
+    Version{"2.1.49.14"}
     zoneStrings{
         "Asia:Rangoon"{
             ec{"Rangoon"}
diff --git a/icu4c/source/data/zone/eo.txt b/icu4c/source/data/zone/eo.txt
index f84c0c1623c..420b16b3345 100644
--- a/icu4c/source/data/zone/eo.txt
+++ b/icu4c/source/data/zone/eo.txt
@@ -1,5 +1,5 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 eo{
-    Version{"2.1.47.82"}
+    Version{"2.1.49.33"}
 }
diff --git a/icu4c/source/data/zone/ms.txt b/icu4c/source/data/zone/ms.txt
index 875f6834e9f..b058d23834e 100644
--- a/icu4c/source/data/zone/ms.txt
+++ b/icu4c/source/data/zone/ms.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ms{
-    Version{"2.1.48.42"}
+    Version{"2.1.49.2"}
     zoneStrings{
         "Africa:Abidjan"{
             ec{"Abidjan"}
diff --git a/icu4c/source/data/zone/ps_PK.txt b/icu4c/source/data/zone/ps_PK.txt
index be543690055..c850f89bb6f 100644
--- a/icu4c/source/data/zone/ps_PK.txt
+++ b/icu4c/source/data/zone/ps_PK.txt
@@ -1,7 +1,7 @@
 // © 2016 and later: Unicode, Inc. and others.
 // License & terms of use: http://www.unicode.org/copyright.html#License
 ps_PK{
-    Version{"2.1.48.67"}
+    Version{"2.1.49.34"}
     zoneStrings{
         "Africa:Harare"{
             ec{"هرارے"}
diff --git a/icu4c/source/test/intltest/dtptngts.cpp b/icu4c/source/test/intltest/dtptngts.cpp
index b0bde3e6ea8..1827f21d290 100644
--- a/icu4c/source/test/intltest/dtptngts.cpp
+++ b/icu4c/source/test/intltest/dtptngts.cpp
@@ -1295,11 +1295,6 @@ void IntlTestDateTimePatternGeneratorAPI::testJjMapping() {
     const Locale* localePtr = DateFormat::getAvailableLocales(locCount);
     for (; locCount-- > 0; localePtr++) {
         const char* localeID = localePtr->getName();
-        if ( logKnownIssue("cldrbug:11894", "locales with known timeData vs short time format mismatch") && ( uprv_strcmp(localeID,"ps_PK")==0
-                || uprv_strcmp(localeID,"ff_Latn_GH")==0 || uprv_strcmp(localeID,"ff_Latn_GM")==0 || uprv_strcmp(localeID,"ff_Latn_LR")==0
-                || uprv_strcmp(localeID,"ff_Latn_SL")==0 ) ) {
-            continue;
-        }
         status = U_ZERO_ERROR;
         LocalPointer<DateTimePatternGenerator> dtpg(DateTimePatternGenerator::createInstance(*localePtr, status));
         if (U_FAILURE(status)) {
diff --git a/icu4j/main/shared/data/icudata.jar b/icu4j/main/shared/data/icudata.jar
index ecd5b779b04..5706bcdef72 100644
--- a/icu4j/main/shared/data/icudata.jar
+++ b/icu4j/main/shared/data/icudata.jar
@@ -1,3 +1,3 @@
 version https://git-lfs.github.com/spec/v1
-oid sha256:fcea7ae2d5d14f5b12404d051c16945676062d8732636b7579eb7ea52a27ea59
-size 14525474
+oid sha256:f5c4f0d2ae6d62092eead5171c68c492e26882724c1d36e1b8bae11b9751788e
+size 14112126
diff --git a/icu4j/main/shared/data/icutzdata.jar b/icu4j/main/shared/data/icutzdata.jar
index 87a2e5c9e08..ec72a994365 100644
--- a/icu4j/main/shared/data/icutzdata.jar
+++ b/icu4j/main/shared/data/icutzdata.jar
@@ -1,3 +1,3 @@
 version https://git-lfs.github.com/spec/v1
-oid sha256:ba0d976bc7c765d905dd1aa455063ed955bcb4d7c028b51dd5ef1e6a4a868c01
+oid sha256:640e2f8cc8e92949262848cbfa9fef63503e989717a4d4c36391fb8db79acb12
 size 94046
diff --git a/icu4j/main/tests/core/src/com/ibm/icu/dev/test/format/DateTimeGeneratorTest.java b/icu4j/main/tests/core/src/com/ibm/icu/dev/test/format/DateTimeGeneratorTest.java
index 392b5183479..e96df688247 100644
--- a/icu4j/main/tests/core/src/com/ibm/icu/dev/test/format/DateTimeGeneratorTest.java
+++ b/icu4j/main/tests/core/src/com/ibm/icu/dev/test/format/DateTimeGeneratorTest.java
@@ -1689,11 +1689,6 @@ public class DateTimeGeneratorTest extends TestFmwk {
         ULocale[] locales = DateFormat.getAvailableULocales();
         for (ULocale locale: locales) {
             String localeID = locale.getName();
-            if ( logKnownIssue("cldrbug:11894", "locales with known timeData vs short time format mismatch") &&
-                    ( localeID.equals("ps_PK") || localeID.equals("ff_Latn_GH") || localeID.equals("ff_Latn_GM")
-                    || localeID.equals("ff_Latn_LR") || localeID.equals("ff_Latn_SL") ) ) {
-                continue;
-            }
             DateTimePatternGenerator dtpg = DateTimePatternGenerator.getInstance(locale);
             DateFormat dfmt = DateFormat.getTimeInstance(DateFormat.SHORT, locale);
             String shortPattern = ((SimpleDateFormat)dfmt).toPattern();
diff --git a/icu4j/main/tests/core/src/com/ibm/icu/dev/test/util/ICUResourceBundleTest.java b/icu4j/main/tests/core/src/com/ibm/icu/dev/test/util/ICUResourceBundleTest.java
index 66fd19e19f7..28f77b7dc8e 100644
--- a/icu4j/main/tests/core/src/com/ibm/icu/dev/test/util/ICUResourceBundleTest.java
+++ b/icu4j/main/tests/core/src/com/ibm/icu/dev/test/util/ICUResourceBundleTest.java
@@ -710,11 +710,6 @@ public final class ICUResourceBundleTest extends TestFmwk {
             localCountryExceptions.add("ti_ER");
             localCountryExceptions.add("ti_ET");
         }
-        if (logKnownIssue("cldrbug:11895",
-                "No localized region name for ceb_PH, eo_001")) {
-            localCountryExceptions.add("ceb_PH");
-            localCountryExceptions.add("eo_001");
-        }
 
         Set<String> localLangExceptions = new HashSet<String>();
         if (logKnownIssue("cldrbug:8903", "No localized language name for nmg, nds")) {