diff --git a/.github/workflows/icu_envtest.yml b/.github/workflows/icu_envtest.yml
index 198fd49968d..b88aac33bb0 100644
--- a/.github/workflows/icu_envtest.yml
+++ b/.github/workflows/icu_envtest.yml
@@ -14,6 +14,9 @@ on:
   schedule:
     # This cron schedule is set to run 10:23 UTC every SAT
     - cron: '23 10 * * SAT'
+    # In addition, during the major release cycle (in March/April, September/October),
+    # this cron schedule is set to run 10:21 UTC every Workday and Sunday.
+    - cron: '21 10 * MAR,APR,SEP,OCT MON-FRI,SUN'
 
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   contents: read