diff --git a/icu4c/source/common/unicode/uvernum.h b/icu4c/source/common/unicode/uvernum.h
index f51bd266f7a..eb7c50f3856 100644
--- a/icu4c/source/common/unicode/uvernum.h
+++ b/icu4c/source/common/unicode/uvernum.h
@@ -59,13 +59,13 @@
  *  This value will change in the subsequent releases of ICU
  *  @stable ICU 2.6
  */
-#define U_ICU_VERSION_MINOR_NUM 0
+#define U_ICU_VERSION_MINOR_NUM 1
 
 /** The current ICU patchlevel version as an integer.
  *  This value will change in the subsequent releases of ICU
  *  @stable ICU 2.4
  */
-#define U_ICU_VERSION_PATCHLEVEL_NUM 1
+#define U_ICU_VERSION_PATCHLEVEL_NUM 0
 
 /** The current ICU build level version as an integer.
  *  This value is for use by ICU clients. It defaults to 0.
@@ -132,7 +132,7 @@
  *  This value will change in the subsequent releases of ICU
  *  @stable ICU 2.4
  */
-#define U_ICU_VERSION "75.0.1"
+#define U_ICU_VERSION "75.1"
 
 /**
  * The current ICU library major version number as a string, for library name suffixes.
@@ -151,7 +151,7 @@
 /** Data version in ICU4C.
  * @internal ICU 4.4 Internal Use Only
  **/
-#define U_ICU_DATA_VERSION "75.0.1"
+#define U_ICU_DATA_VERSION "75.1"
 #endif  /* U_HIDE_INTERNAL_API */
 
 /*===========================================================================
diff --git a/icu4c/source/configure b/icu4c/source/configure
index b52aa815aec..6a1719bfd19 100755
--- a/icu4c/source/configure
+++ b/icu4c/source/configure
@@ -1,6 +1,6 @@
 #! /bin/sh
 # Guess values for system-dependent variables and create Makefiles.
-# Generated by GNU Autoconf 2.69 for ICU 75.0.1.
+# Generated by GNU Autoconf 2.69 for ICU 75.1.
 #
 # Report bugs to <http://icu-project.org/bugs>.
 #
@@ -582,8 +582,8 @@ MAKEFLAGS=
 # Identity of this package.
 PACKAGE_NAME='ICU'
 PACKAGE_TARNAME='International Components for Unicode'
-PACKAGE_VERSION='75.0.1'
-PACKAGE_STRING='ICU 75.0.1'
+PACKAGE_VERSION='75.1'
+PACKAGE_STRING='ICU 75.1'
 PACKAGE_BUGREPORT='http://icu-project.org/bugs'
 PACKAGE_URL='http://icu-project.org'
 
@@ -1374,7 +1374,7 @@ if test "$ac_init_help" = "long"; then
   # Omit some internal or obsolete options to make the list less imposing.
   # This message is too long to be a string in the A/UX 3.1 sh.
   cat <<_ACEOF
-\`configure' configures ICU 75.0.1 to adapt to many kinds of systems.
+\`configure' configures ICU 75.1 to adapt to many kinds of systems.
 
 Usage: $0 [OPTION]... [VAR=VALUE]...
 
@@ -1441,7 +1441,7 @@ fi
 
 if test -n "$ac_init_help"; then
   case $ac_init_help in
-     short | recursive ) echo "Configuration of ICU 75.0.1:";;
+     short | recursive ) echo "Configuration of ICU 75.1:";;
    esac
   cat <<\_ACEOF
 
@@ -1579,7 +1579,7 @@ fi
 test -n "$ac_init_help" && exit $ac_status
 if $ac_init_version; then
   cat <<\_ACEOF
-ICU configure 75.0.1
+ICU configure 75.1
 generated by GNU Autoconf 2.69
 
 Copyright (C) 2012 Free Software Foundation, Inc.
@@ -2217,7 +2217,7 @@ cat >config.log <<_ACEOF
 This file contains any messages produced by compilers while
 running configure, to aid debugging if configure makes a mistake.
 
-It was created by ICU $as_me 75.0.1, which was
+It was created by ICU $as_me 75.1, which was
 generated by GNU Autoconf 2.69.  Invocation command line was
 
   $ $0 $@
@@ -8292,7 +8292,7 @@ cat >>$CONFIG_STATUS <<\_ACEOF || ac_write_fail=1
 # report actual input values of CONFIG_FILES etc. instead of their
 # values after options handling.
 ac_log="
-This file was extended by ICU $as_me 75.0.1, which was
+This file was extended by ICU $as_me 75.1, which was
 generated by GNU Autoconf 2.69.  Invocation command line was
 
   CONFIG_FILES    = $CONFIG_FILES
@@ -8346,7 +8346,7 @@ _ACEOF
 cat >>$CONFIG_STATUS <<_ACEOF || ac_write_fail=1
 ac_cs_config="`$as_echo "$ac_configure_args" | sed 's/^ //; s/[\\""\`\$]/\\\\&/g'`"
 ac_cs_version="\\
-ICU config.status 75.0.1
+ICU config.status 75.1
 configured by $0, generated by GNU Autoconf 2.69,
   with options \\"\$ac_cs_config\\"
 
diff --git a/icu4c/source/data/misc/icuver.txt b/icu4c/source/data/misc/icuver.txt
index 435da9e8f71..0b7c406a3a5 100644
--- a/icu4c/source/data/misc/icuver.txt
+++ b/icu4c/source/data/misc/icuver.txt
@@ -9,6 +9,6 @@
 // ***************************************************************************
 icuver:table(nofallback){
     CLDRVersion{"45"}
-    DataVersion{"75.0.1.0"}
-    ICUVersion{"75.0.1.0"}
+    DataVersion{"75.1.0.0"}
+    ICUVersion{"75.1.0.0"}
 }
diff --git a/icu4j/main/core/src/main/java/com/ibm/icu/util/VersionInfo.java b/icu4j/main/core/src/main/java/com/ibm/icu/util/VersionInfo.java
index 8e5c7c9fdfd..dbb59601049 100644
--- a/icu4j/main/core/src/main/java/com/ibm/icu/util/VersionInfo.java
+++ b/icu4j/main/core/src/main/java/com/ibm/icu/util/VersionInfo.java
@@ -574,7 +574,7 @@ public final class VersionInfo implements Comparable<VersionInfo>
         UNICODE_15_0   = getInstance(15, 0, 0, 0);
         UNICODE_15_1   = getInstance(15, 1, 0, 0);
 
-        ICU_VERSION   = getInstance(75, 0, 1, 0);
+        ICU_VERSION   = getInstance(75, 1, 0, 0);
         ICU_DATA_VERSION = ICU_VERSION;
         UNICODE_VERSION = UNICODE_15_1;